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  • Demerol may be habit forming. Physical and/or psychological dependence can occur, and withdrawal effects are possible if the medication is stopped suddenly after prolonged or high-dose treatment. NOT stop taking Demerol suddenly without first talking to your physician if you have been taking it continuously for more than 5 to 7 days. your physician may want to gradually reduce the dose.
  • Demerol may increase the effects of other drugs that cause drowsiness, including other pain relievers, alcohol, antihistamines, sedatives (used to treat insomnia), antidepressants, anxiety medicines, and muscle relaxants. Tell your physician about all medicines that you are taking, and NOT take any medicine without first talking to your physician. ...
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  • Demerol may be habit forming and should only be used under close supervision if there is a history of alcohol or drug addiction.
  • Before taking this medication, tell your physician if you have ...
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  • Take Demerol exactly as directed by your physician. If you NOT understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water. ...
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  • Seek emergency medical attention if an overdose is suspected.
  • Symptoms of a Demerol overdose include slow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold and clammy skin, and small pupils. ...
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  • Use caution when driving, operating machinery, or performing other hazardous activities. Demerol may cause drowsiness. If you experience drowsiness, avoid these activities.
  • Avoid alcohol while taking Demerol. Alcohol may increase the drowsiness and dizziness caused by Demerol and could be dangerous. ...
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  • If you experience any of the following serious side effects, stop taking Demerol and seek emergency medical attention or contact your physician immediately:
    -- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); ...
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